Searchable abstracts of presentations at key conferences in endocrinology

ea0029p821 | Endocrine tumours and neoplasia | ICEECE2012

Expression of ErbB2 in craniopharyngiomas: Possible therapeutic implications

Zuhur Sayid Shafi , Tanik Canan , Velet Selvinaz , Musluman Ahmet Murat , Kabukcuoglu Fevziye , Altuntas Yuksel

Background: Currently, there is no satisfying treatment option other than gross total or subtotal resection in combination with adjuvant radiotherapy for the treatment of craniopharyngiomas. However, recurrence could occur in a substantial proportion of craniopharyngiomas despite gross total resection and radiotherapy. Human epidermal growth factor receptor 2 (HER-2/ErbB2) overexpression was determined in various human carcinomas and is associated with aggressive clinical beha...